Stereoselective synthesis of (-)-lepadins A-C.
نویسندگان
چکیده
A concise synthesis of the marine alkaloids (-)-lepadins A-C from a phenylglycinol-derived tricyclic lactam is reported. Key steps from the stereochemical standpoint involve stereoselective cyclocondensation, double bond hydrogenation, oxazolidine opening, hydroboration-oxidation, and Horner-Wadsworth-Emmons reactions.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 94 شماره
صفحات -
تاریخ انتشار 2013